Marilyn Monroe
Reason for leaving cinema:
Drug overdose / suicide / murder (depending on who you ask)
Final Film: The Misfits
Although Marilyn worked on one more film, Something's Got to Give, The Misfits was her final completed role. It is one of her finest bits of acting and earned her a Golden Globe. She certainly could draw inspiration for her character from her car crash of a personal life, including her recently derailed marriage to Arthur Miller who wrote the script.